PRODUCT Properties
| Melting point: | 149° |
| Boiling point: | 567.4±50.0 °C(Predicted) |
| alpha | 20Cd -165° (benzene); -226° (chloroform). Also reported as -254 ± 7° (chloroform) (Toribara) |
| Density | 1.373±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, protect from light |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder |
| pka | 7.34±0.20(Predicted) |
| color | Purple |
Description and Uses
Alkannin (cas# 23444-65-7) inhibits proliferation, migration and invasion of human Huh7 and Hep3B2.1-7 hepatocellular carcinoma cells via regulation of miR92a. It is also useful in the application of macromolecular crowding to investigate naphthoquinones shikonin, naphthazarin and related analogs for treatment of dermal scars in human.
Safety
| Toxicity | LD50 in male, female mice, rats (g/kg): 3.0 ± 1.0; 3.1 ± 0.1; >1.0 orally (Majlathova) |
