Shikonin , 97% , 517-89-5
Synonym(s):
Isoarnebin 4;Shikonin S;Tokyo Violet;(±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone;(±)-Alkannin
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB702.40 | In Stock |
|
| 250mg | RMB1192.80 | In Stock |
|
| 1g | RMB3100.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 148℃ |
| Boiling point: | 567.4±50.0 °C(Predicted) |
| Density | 1.373±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO : ≥ 31 mg/mL (107.53 mM); |
| pka | 7.34±0.20(Predicted) |
| form | Red crystalline solid. |
| color | Brown |
| LogP | 4.350 (est) |
| CAS DataBase Reference | 517-89-5(CAS DataBase Reference) |
Description and Uses
Shikonin could be found in the plant of Lithospermum erythrorhizon Sieb. et. Zucc
and Arnebia euchroma (Royle) Johnst. It could also be produced using plant cell
culture techniques. Shikonin is recorded in British Pharmacopoeia as a reference
compound.
Zicao, a traditional Chinese medicine firstly recorded in Shen Nong’s Herbal Classic, has long been used medically in history . Chinese Pharmacopoeia
(Edition 2015) recorded the root of Arnebia euchroma (Royle) Johnst and Arnebia
guttata Bge as Zicao, which is mainly used for inflammatory diseases such as macular
eruptions, measles, sore throat, carbuncles, and burns.
Shikonin has been used as a red dye for centuries and is reported to possess medicinal properties such as antibacterial, anti-inflammatory and antitumor activities. It occurs as an acetyl derivative in the Japanese shikone, Lithospermum erythrorhizon, another member of the Boraginaceae family. It is the (R)-optical isomer of alkannin. Tissue cultures of L. erythrorhizon are used in Japan to manufacture shikonin mainly for cosmetic use. Both alkannin and shikonin are mordant dyes producing violet to gray colors on fabrics. In Japan, shikonin was used to dye fabrics a color known as Tokyo Violet. Shikalkin the racemate, has been synthesized.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Risk Statements | 20/21/22-50/53-20 |
| Safety Statements | 26-36/37/39-61 |
| RIDADR | 3077 |
| HS Code | 29146990 |
| Hazardous Substances Data | 517-89-5(Hazardous Substances Data) |
