A0800312
α-Bromodiphenylmethane , ≥96.0%(GC) , 776-74-9
Synonym(s):
Benzhydryl bromide;Diphenylbromomethane
CAS NO.：776-74-9
Empirical Formula: C13H11Br
Molecular Weight: 247.13
MDL number: MFCD00000134
EINECS: 212-279-8
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 35-39 °C(lit.) |
| Boiling point: | 184 °C20 mm Hg(lit.) |
| Density | 0,9 g/cm3 |
| refractive index | 1.6290 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | 0.45g/l |
| form | powder to lump to clear liquid |
| color | White to cream to yellow to orange to brown crystals or fused solid |
| PH | 2 (H2O, 20℃)(saturated aqueous solution) |
| Water Solubility | Insoluble |
| Sensitive | Moisture Sensitive |
| BRN | 638544 |
| CAS DataBase Reference | 776-74-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1,1'-(bromomethylene)bis-(776-74-9) |
| EPA Substance Registry System | Benzene, 1,1'-(bromomethylene)bis- (776-74-9) |
Description and Uses
Benzhydryl bromide is a halogenated building block. Benzhydryl group was preferred to the commoner benzyl to protect 2-nitrophenol in the Bartoli (vinyl Grignard) synthesis of 7-hydroxyindole. Protection was by reaction with the phenol in the presence of potassium carbonate in acetone; deprotection of the indole was by hydrogenolysis.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H318-H314 |
| Precautionary statements | P280-P305+P351+P338-P310-P309-P260-P264-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501 |
| Hazard Codes | C |
| Risk Statements | 34-37 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 1770 8/PG 2 |
| WGK Germany | 3 |
| RTECS | PA5350000 |
| F | 19-21 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29036990 |
