A0741612
2-Amino-4,5-difluorobenzoic acid , 98% , 83506-93-8
Synonym(s):
2-Amino-4,5-difluorobenzoic acid
CAS NO.:83506-93-8
Empirical Formula: C7H5F2NO2
Molecular Weight: 173.12
MDL number: MFCD00077509
EINECS: 627-164-1
Pack Size | Price | Stock | Quantity |
1G | RMB24.00 | In Stock |
|
5G | RMB89.60 | In Stock |
|
25G | RMB342.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 181-185 °C |
Boiling point: | 326.8±42.0 °C(Predicted) |
Density | 1.536±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
pka | 4.54±0.10(Predicted) |
form | Liquid |
color | Clear colorless to straw |
BRN | 2834162 |
CAS DataBase Reference | 83506-93-8(CAS DataBase Reference) |
Description and Uses
2-Amino-4,5-difluorobenzoic acid is a benzoic acid derivative used as an intermediate in icotinib. icotinib is an effective and highly selective oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) for the treatment of patients with advanced non-small-cell lung cancer (NSCLC) who have failed prior chemotherapy.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38-36-26 |
Safety Statements | 26-36-36/37/38 |
WGK Germany | 3 |
HazardClass | IRRITANT |
HS Code | 29224999 |