A0741612
2-Amino-4,5-difluorobenzoic acid , 98% , 83506-93-8
Synonym(s):
2-Amino-4,5-difluorobenzoic acid
CAS NO.：83506-93-8
Empirical Formula: C7H5F2NO2
Molecular Weight: 173.12
MDL number: MFCD00077509
EINECS: 627-164-1
| Pack Size | Price | Stock | Quantity |
| 1G | RMB24.00 | In Stock |
|
| 5G | RMB89.60 | In Stock |
|
| 25G | RMB342.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 181-185 °C |
| Boiling point: | 326.8±42.0 °C(Predicted) |
| Density | 1.536±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Liquid |
| pka | 4.54±0.10(Predicted) |
| color | Clear colorless to straw |
| BRN | 2834162 |
Description and Uses
2-Amino-4,5-difluorobenzoic acid is a benzoic acid derivative used as an intermediate in icotinib. icotinib is an effective and highly selective oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) for the treatment of patients with advanced non-small-cell lung cancer (NSCLC) who have failed prior chemotherapy.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-36-26 |
| Safety Statements | 26-36-36/37/38 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29224999 |
