Carboplatin , 99.95%metalsbasis , 41575-94-4

Synonym(s):
cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin;cis-Diammine(1,1-cyclobutanedicarboxylato) platinum;Carboplatin;Carboplatin - CAS 41575-94-4 - Calbiochem

CAS NO.：41575-94-4

Empirical Formula: C6H12N2O4Pt

Molecular Weight: 371.25

MDL number: MFCD00070464

EINECS: 255-446-0

PRODUCT Properties

• Melting point: 228-230°C
• storage temp.: 2-8°C
• solubility: Sparingly soluble in water, very slightly soluble in acetone and in ethanol (96 per cent).
• form: crystal
• color: white
• Water Solubility: Soluble in water.
• Merck: 14,1822
• Stability: Stable. Incompatible with strong oxidizing agents.
• InChI: InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2
• InChIKey: OLESAACUTLOWQZ-UHFFFAOYSA-L
• SMILES: C12(CCC1)C(=O)O[Pt]OC2=O.N.N
• EPA Substance Registry System: Carboplatin (41575-94-4)

Description and Uses

Carboplatin is a second generation, platinum-containing antineoplastic agent with significantly reduced nephro-, neuro-, and ototoxicity in comparison to cisplatin. It is effective in the treatment of advanced ovarian carcinoma of epithelial origin and small cell carcinoma of the lung.

antitumor agent,

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302+H312+H332-H317-H334-H340-H360
• Precautionary statements: P201-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313
• Hazard Codes: T
• Risk Statements: 46-61-20/21/22-42/43-20/21
• Safety Statements: 53-22-26-36/37/39-45
• RIDADR: 2811
• WGK Germany: 3
• RTECS: TP2300000
• HS Code: 28439000
• Hazardous Substances Data: 41575-94-4(Hazardous Substances Data)
• Toxicity: LD50 in mice (mg/kg): 150 i.p., 140 i.v.; in rats (mg/kg): 85 i.v. (Lelieveld)