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A0640456

Colchicinesolution , 1mg/mLinacetonitrile,certifiedreferencematerial,ampuleof1mL1ml , 64-86-8

Synonym(s):
(S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide;Colchicine;Colchicine, Colchicum autumnale - CAS 64-86-8 - Calbiochem

CAS NO.:64-86-8

Empirical Formula: C22H25NO6

Molecular Weight: 399.44

MDL number: MFCD00078484

EINECS: 200-598-5

Pack Size Price Stock Quantity
1ml RMB1039.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 150-160 °C (dec.)(lit.)
alpha  -250 º (c=1, alcohol)
Boiling point: 522.37°C (rough estimate)
Density  1.2770 (rough estimate)
refractive index  1.5614 (estimate)
storage temp.  2-8°C
solubility  H2O: 10 mg/mL
pka 12.36(at 20℃)
form  powder
color  white to yellow with a green cast
Water Solubility  45 g/L (20 ºC)
Sensitive  Light Sensitive
Merck  14,2471
BRN  2228813
BCS Class 3
Stability: Stable. Light sensitive. Incompatible with strong oxidizing agents.
InChIKey IAKHMKGGTNLKSZ-INIZCTEOSA-N
LogP 1.300

Description and Uses

Colchicine is a pale-yellow powder that is obtained from various species of Colchicum, primarily Colchicum autumnale L. Its total chemical synthesis has been achieved, but the primary source of colchicine currently remains alcohol extraction of the alkaloid from the corm and seed of C. autumnale L. It darkens on exposure to light and possesses

anti-inflammatory agent, mitosis inhibitor

Safety

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H300-H340
Precautionary statements  P202-P264-P270-P280-P301+P310-P405
Hazard Codes  T+,T,Xi
Risk Statements  26/28-41-46
Safety Statements  13-45-36/37/39-28-26-53
RIDADR  UN 1544 6.1/PG 1
WGK Germany  3
RTECS  GH0700000
TSCA  Yes
HazardClass  6.1
PackingGroup  I
HS Code  29399990
Toxicity LD50 in rats (mg/kg): 1.6 i.v. (Rosenbloom, Ferguson); in mice (mg/kg): 4.13 i.v. (Beliles)

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