PRODUCT Properties
Melting point: | 298° |
alpha | D20 -47° (pyridine); D20 -32° (10% aq pyridine) |
Boiling point: | 466.08°C (rough estimate) |
Density | 1.3597 (rough estimate) |
refractive index | 1.5376 (estimate) |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | Aqueous Base (Slightly), DMSO (Slightly, Heated), Pyridine (Slightly, Sonicated) |
pka | 6.45±0.20(Predicted) |
form | Solid |
color | White to Light Brown |
λmax | 271nm(MeOH)(lit.) |
Description and Uses
Genistein 4''-β-D-glucopyranoside is a metabolite of Genistein (G350000), which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |
Safety Statements | 22-24/25 |
HS Code | 29329990 |