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A5418312

Matrine , Analysis of standard products, ≥98% , 519-02-8

Synonym(s):
Matridin-15-one;Sophocarpidine

CAS NO.:519-02-8

Empirical Formula: C15H24N2O

Molecular Weight: 248.36

MDL number: MFCD00210527

EINECS: 610-750-6

Pack Size Price Stock Quantity
20MG RMB78.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 77 C
Boiling point: 86-88C/2,5Torr
alpha  D20 +38° (alc)
Density  1,191g/cm
refractive index  1,536
storage temp.  Sealed in dry,2-8°C
solubility  Soluble in Water (up to 25 mg/ml)
form  solid
pka 9.47±0.20(Predicted)
color  White
optical activity +37.926 (c 1.69, H2O)
Merck  14,5759
Stability: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
LogP 1.440 (est)

Description and Uses

Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens Aiton. The extraction process involves the use of organic solvents on dry roots, plants, and fruits of kushen 苦参 (Sophora flavescens Ait). Matrine is also present in S. alopecuroides L. and S. subprostrata Chun et T. Chen.
Chinese medicine Radix Sophora flavescentis have dampness eliminating insecticide and diuretic effects. Sophora flavescens is used for heat dysentery, hemafecia, jaundice and anuria, red leukorrhea, vulva pruritus, eczema, wet sores, skin itching, scabies, ringworm, and trichomonas vaginitis. Sophora flavescens is recorded in the ancient Materia Medica. “Southern Yunnan Materia Medica” also recorded the effects of Saphora flavescens.
Sophora flavescens is a species of Sophora japonica and is distributed in temperate and subtropical regions. Sophora flavescens is widely distributed in China, mainly in the north of Hebei, the west of Henan, and southwest of Shandong, Anhui, Hubei, and Guizhou.

(+)-Matrine is an alkaloid compound extracted from the roots of Sophora species which maintain anti-inflammatory, anti-cancer and a host of other positive pharmacological effects. Apoptotic agent.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  20/21/22-37/38-41-48-22
Safety Statements  22-26-36/37/39-45-36/37
WGK Germany  3
RTECS  OQ1754000
HS Code  13021990

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