Home Categories Biochemical Engineering Icariin
A5070212

Icariin , 96% , 489-32-7

Synonym(s):
4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

CAS NO.:489-32-7

Empirical Formula: C33H40O15

Molecular Weight: 676.66

MDL number: MFCD00210516

EINECS: 610-440-0

Pack Size Price Stock Quantity
250MG RMB74.40 In Stock
1G RMB199.20 In Stock
200mg RMB440.00 In Stock
5G RMB740.00 In Stock
25G RMB2800.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 223-225 ºC
alpha  D15 -87.09° (in pyridine)
Boiling point: 948.5±65.0 °C(Predicted)
Density  1.55
RTECS  DJ2980500
storage temp.  2-8°C
solubility  DMSO: soluble50mg/mL, clear, colorless to dark yellow
form  Powder
pka 5.90±0.40(Predicted)
color  light yellow to yellow
λmax 350nm(MeOH)(lit.)
Merck  14,3617
Stability: Light Sensitive
InChIKey TZJALUIVHRYQQB-XLRXWWTNSA-N
LogP 1.736 (est)

Description and Uses

Icariin has been used:

  • in the preparation of topical treatment to determine its effects on the improvement of cutaneous wound healing in rats
  • to test its analgesic effects on lower back pain (LBP) in rats
  • as a potential treatment in osteoporosis condition in rats
  • to study its effects on palmitate (PA)-induced insulin resistance in skeletal muscle C2C12 myotubes
  • as a neuroprotective agent to study its effects on amyloid-β (Aβ)-induced neuronal insulin resistance in human neuroblastoma SK-N-MC cells

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Safety Statements  24/25
WGK Germany  3
HS Code  29389090

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