N-Acetylneuraminic acid , 98% , 131-48-6

Synonym(s):
NAN;Sialic acid;NANA;Lactaminic acid;NANA, Lactaminic Acid, Sialic Acid

CAS NO.：131-48-6

Empirical Formula: C11H19NO9

Molecular Weight: 309.27

MDL number: MFCD00006620

EINECS: 205-023-1

PRODUCT Properties

• Melting point: 184-186 °C
• alpha: -32 º (c=2,water)
• Boiling point: 449.56°C (rough estimate)
• Density: 1.3580 (rough estimate)
• refractive index: -32 ° (C=1, H2O)
• storage temp.: -20°C
• solubility: 50 g/L (20°C)
• pka: 2.41±0.54(Predicted)
• form: synthetic, crystalline
• color: White to Off-White
• optical activity: -32
• Water Solubility: 50 g/L (20 ºC)
• Sensitive: Air Sensitive
• Merck: 14,8484
• BRN: 1716283
• Stability: Stable. Incompatible with strong oxidizing agents.
• InChIKey: SQVRNKJHWKZAKO-PFQGKNLYSA-N
• LogP: -1.897 (est)
• CAS DataBase Reference: 131-48-6(CAS DataBase Reference)
• EPA Substance Registry System: Neuraminic acid, N-acetyl- (131-48-6)

Description and Uses

N-acetylneuraminic acid is an N-acyl derivative of neuraminic or acid amino sugar derivative, derived from N-acetylmannosamine and pyruvic acid. It is an important constituent of glycoproteins and glycolipids. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria.

N-Acetylneuraminic acid is an integral part of sialic acids (SAs), important functional sugars that play an important role in maintaining and improving brain health, detoxification, antibacterial, and immune enhancement. n-Acetylneuraminic acid is biologically useful for neurotransmission, leukocyte extravasation, viral or bacterial infection, and carbohydrate-protein recognition. n- Acetylneuraminic acid is used to study its biochemistry, metabolism and absorption in vivo and in vitro.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319
• Precautionary statements: P264-P280-P305+P351+P338-P337+P313
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• F: 3-10-23
• Hazard Note: Irritant
• TSCA: Yes
• HS Code: 29329970