Pregnenolone Acetate , >99.0%(HPLC) , 1778-02-5

Synonym(s):
3β-Acetoxy-5-pregnen-20-one;5-Pregnen-3β-ol-20-one acetate

CAS NO.：1778-02-5

Empirical Formula: C23H34O3

Molecular Weight: 358.51

MDL number: MFCD00003627

EINECS: 217-212-6

PRODUCT Properties

• Melting point: 149-152 °C(lit.)
• Boiling point: 430.93°C (rough estimate)
• alpha: 22 º (c=2, C2H5OH 23 ºC)
• Density: 1.0816 (rough estimate)
• refractive index: 1.4700 (estimate)
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
• form: Solid
• color: White
• optical activity: [α]20/D +19°, c = 1 in ethanol
• Merck: 14,7733
• BRN: 2062850
• InChIKey: CRRKVZVYZQXICQ-RJJCNJEVSA-N
• CAS DataBase Reference: 1778-02-5(CAS DataBase Reference)
• NIST Chemistry Reference: 3Beta-acetoxypregn-5-en-20-one(1778-02-5)

Description and Uses

Pregnenolone acetate is an intermediate in the synthesis of progesterone. It is uses as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It has also been shown to stimulate locomotor activity and neuronal function in rats.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• HS Code: 29153900