PRODUCT Properties
| Melting point: | -6.35°C (estimate) |
| Boiling point: | 80-81 °C (10 mmHg) |
| Density | 0.822 |
| refractive index | 1.449-1.453 |
| Flash point: | 60°C |
| storage temp. | Flammables area |
| form | Liquid |
| Specific Gravity | 0.816 |
| color | Clear yellow |
| Water Solubility | Insoluble in water. |
| BRN | 1734594 |
Description and Uses
One-step synthesis of carbametacyclophane 3 from 1,9-decadiyne and diethyl acetylenedicarboxylate is described. The use of 1,9-decadiyne as a nucleophile led only to the monoalkynylation product, a selectivity that would be difficult to achieve with a catalytic in situ metalation process. 1,9-decadiyne reacts with iodobenzene (excess) to afford the bis-Sonogashira coupling product in excellent yield. 1,9-Decadiyne was dihydrated and gave 2,9-decanedione in 92% yield.
Safety
| Symbol(GHS) |   GHS08,GHS02 |
| Signal word | Danger |
| Hazard statements | H226-H227-H304 |
| Precautionary statements | P210-P280-P301+P310+P331-P370+P378-P403+P235-P405-P501-P240-P241-P280a-P303+P361+P353-P501a |
| Risk Statements | 10 |
| Safety Statements | 16 |
| RIDADR | 1993 |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29012900 |
