(R)-(+)-2-Chloropropionic Acid , >98.0%(GC)(T) , 7474-05-7

CAS NO.：7474-05-7

Empirical Formula: C3H5ClO2

Molecular Weight: 108.52

MDL number: MFCD00064204

EINECS: 626-432-5

PRODUCT Properties

• Melting point: -12°C
• alpha: 14 º (neat)
• Boiling point: 185-188 °C (lit.)
• Density: 1.258 g/mL at 20 °C (lit.)
• refractive index: n20/D 1.4345(lit.)
• Flash point: 140 °F
• storage temp.: −20°C
• solubility: soluble in Chloroform, Methanol
• form: clear liquid
• pka: 2.96±0.10(Predicted)
• color: Colorless to Almost colorless
• optical activity: [α]20/D +14°, neat
• BRN: 1720258

Description and Uses

(R)-(+)-2-Chloropropionic acid can be used as a starting material in the synthesis of:???????

• Thiolactic acid, a key intermediate, which is used for the preparation of 2(R),5(S)-oxathiolanones by reacting with pivalaldehyde.???????
• (R)-2-chloropropionyl chloride, a key intermediate, which is utilized in the synthesis of (R)-4,5-dihydro-5-methylpyridazin-3(2H)-one derivative with pyrazolopyridine ring as a potential phosphodiesterase inhibitor.???????
• 2-Chloropropionamide derivatives as protein disulfide isomerase (PID) inhibitors.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H314
• Precautionary statements: P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
• Hazard Codes: C
• Risk Statements: 22-35
• Safety Statements: 23-26-28-36-45
• RIDADR: UN 2511 8/PG 3
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• HS Code: 29159000