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S9640148

forsynthesis , 553-26-4

Synonym(s):
11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-D4;11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-d4 (9,11,12,12-d4);17-Hydroxycorticosterone-9,11,12,12-d4;17-Hydroxycorticosterone-D4;4-Pregnene-11β,17α,21-triol-3,20-dione-D4

CAS NO.:553-26-4

Empirical Formula: C21H26D4O4

Molecular Weight: 350.49

MDL number: MFCD00144010

EINECS: 694-327-1

Pack Size Price Stock Quantity
10g RMB259.96 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 211-214 °C
Flash point: 9℃
storage temp.  -20°C Freezer
solubility  DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly, Heated), Water
form  Solid
color  White to Off-White

Description and Uses

Hydrocortisone-d4 is intended for use as an internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS. Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson''s disease.

Anti-inflammatory hormone

Safety

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  Xn,T,F
Risk Statements  63-39/23/24/25-23/24/25-11
Safety Statements  36/37-45-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3

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