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S9205514

50679-08-8

Synonym(s):
α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

CAS NO.:50679-08-8

Empirical Formula: C32H41NO2

Molecular Weight: 471.67

MDL number: MFCD00079622

EINECS: 256-710-8

Pack Size Price Stock Quantity
5g RMB959.05 In Stock
25g RMB3818.54 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 145-152 °C
Boiling point: 572.76°C (rough estimate)
Density  1.0488 (rough estimate)
refractive index  1.6310 (estimate)
storage temp.  2-8°C
solubility  chloroform: soluble250 mg plus 5 ml of solvent, clear to very slightly hazy, colorless to faintly yellow
pka pKa 9.21(H2O t = 25 I = 0.025) (Uncertain)
form  Solid
color  White to Off-White
Water Solubility  0.001 g/100 mL (30 ºC)

Description and Uses

Terfenadine has been used to study the role of histamine in itch related to proteinase-activated receptors (PARs) in mice. Terfenadine has also been used to block histamine receptor type 1 to study the pathogenesis of 2,4-dinitrobenzene sulfonic acid (DNBS)-induced ulcerative colitis in rats.

Safety

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H413
Precautionary statements  P273-P501
Safety Statements  24/25
WGK Germany  2
RTECS  TM4969000
HS Code  29333999
Toxicity LD50 orally in mice: >2000 mg/kg (Carr, Meyer)

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