Ebastine , 98% , 90729-43-4

Synonym(s):
1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone

CAS NO.：90729-43-4

Empirical Formula: C32H39NO2

Molecular Weight: 469.66

MDL number: MFCD00865661

EINECS: 635-609-6

PRODUCT Properties

• Melting point: 80-82°C
• Boiling point: 596.3±50.0 °C(Predicted)
• Density: 1.09±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Slightly soluble in chloroform, methanol.
• form: solid
• pka: 8.19±0.10(Predicted)
• color: white
• Merck: 14,3484
• CAS DataBase Reference: 90729-43-4(CAS DataBase Reference)

Description and Uses

Ebastine is a new once-daily histamine Hl-receptor antagonist with no sedative effects or autonomic impairment at therapeutic doses. It is reported to be effective in the treatment of hay fever, perennial rhinitis, and uticaria. Ebastine's antihistamine activity is attributed to its carboxylic acid metabolite carebastine.

A nonsedating type histamine H1-receptor antagonist. Antihistaminic

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H303
• Precautionary statements: P270-P301+P312-P403-P501c
• WGK Germany: 3
• RTECS: EL8140000
• HS Code: 2933.39.9200