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S9020114

≥85%(HPLC) , 11079-53-1

CAS NO.:11079-53-1

Empirical Formula: C35H52O4

Molecular Weight: 536.78

MDL number: MFCD01861497

EINECS: 601-000-9

Pack Size Price Stock Quantity
250μG RMB2514.38 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 79-80℃
alpha  D18 +41° (in ethanol)
Boiling point: 616.8±55.0 °C(Predicted)
Density  1.010±0.06 g/cm3 (20 ºC 760 Torr)
Flash point: 9℃
storage temp.  -20°C
form  solution
pka 4.8 (50% aq ethanol)
CAS DataBase Reference 11079-53-1

Description and Uses

St. John’s wort is a widely consumed herbal preparation which has been claimed to have a number of medicinal properties. It contains a number of known lipid signalling mediators, including chlorogenic acid, hypericin, hyperforin, and I3,II8-biapigenin. Hyperforin exhibits two activities which may alter the action of other concurrent medications. It inhibits the activity of several CYP450 enzymes, with CYP2D6 being the most sensitive with an IC50 of about 10 μg/ml. Hyperforin is also a ligand for the steroid X receptor (SXR). Since one activity of this receptor is the induction of CYP450 expression, the exact nature of hyperforin’s drug-drug interactions must be evaluated on a case-by-case basis. However, these interactions certainly complicate its use as a human therapeutic.[Cayman Chemical]

Safety

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45
RIDADR  UN1230 - class 3 - PG 2 - Methanol
WGK Germany  3
HS Code  29144000
Hazardous Substances Data 11079-53-1(Hazardous Substances Data)

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