S8910514
powder , 136632-32-1
CAS NO.：136632-32-1
Empirical Formula: C19H35N3O4S1
Molecular Weight: 401.56
MDL number: MFCD00065506
EINECS: 603-969-3
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1233.46 | In Stock |
|
| 25mg | RMB4668.74 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | −20°C |
| solubility | Soluble in ethanol at 20mg/ml |
| form | powder |
| color | white |
| BRN | 7693643 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
Description and Uses
ALLM (136632-32-1) is a cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki?= 120 nM, calpain II, Ki?= 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM).1?Weak inhibitor of the chymotrypsin-like activity of the proteasome.2?Cell permeable.
Calpain inhibitor II is a cell-permeable peptide that restricts the activity of calpain, cathepsin L and cathepsin B. Calpain inhibitor II also prevents the methylmercury-induced cell death of cultured rat cerebellar neurons.
