≥97%(HPLC) , 100938-10-1

Synonym(s):
(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrochloride hydrate

CAS NO.：100938-10-1

Empirical Formula: C21H39ClN4O8

Molecular Weight: 511.01

MDL number: MFCD00058071

EINECS: 999-999-2

PRODUCT Properties

• Melting point: 202-205 °C
• storage temp.: -20°C
• solubility: methanol: 5 mg/mL, clear, colorless
• form: White to off-white powder.
• color: White to off-white
• BRN: 8888370

Description and Uses

Amastatin is a slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of human serum AP-A (glutamyl AP; IC50 = 0.54 μg/ml) but not of AP-B (arginine AP). It also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 μM). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.[Cayman Chemical]

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P271-P261-P280
• WGK Germany: 3
• F: 10
• HS Code: 2924190090