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S8864019

AldrichCPR , 4921-82-8

CAS NO.:4921-82-8

Empirical Formula: C14H12N2OS

Molecular Weight: 256.32

MDL number: MFCD00022118

Pack Size Price Stock Quantity
1g RMB1299.72 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 159 °C
Density  1.290±0.06 g/cm3(Predicted)
storage temp.  -20°
solubility  Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
form  solid
pka 9.49±0.70(Predicted)
color  Off-white
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
CAS DataBase Reference 4921-82-8(CAS DataBase Reference)

Description and Uses

TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants?in vitro.2

Safety

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H411-H302
Precautionary statements  P264-P270-P301+P312-P330-P501
HazardClass  IRRITANT
HS Code  2930909899

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