PRODUCT Properties
| Melting point: | 102-104 °C(lit.) |
| Boiling point: | 329.0±25.0 °C(Predicted) |
| Density | 1.798±0.06 g/cm3(Predicted) |
| solubility | Chloroform (Slightly), DMSO (Sparingly), Ethyl Acetate (Sparingly), Methanol (Slightly) |
| form | crystalline powder |
| color | Faint beige |
| Stability: | Moisture Sensitive |
Description and Uses
Methylenebis (phosphonic dichloride) is an organophosphorus compound commonly used in phosphonation reactions. It is more reactive and faster than POCl. This is due to the fact that the phosphorus centre is more electrophilic due to the lack of electron feedback from the CH2 group.
Methylenebis(phosphonic Dichloride) is used as a reagent in synthesis of several organic compounds including that of nucleoside 5'-methylenebis(phosphonate)s and bisphosphonated glycopeptide prodrugs for the treatment of osteomyelitis.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 |
| Hazard Codes | C |
| Risk Statements | 14-34 |
| Safety Statements | 26-27-36/37/39-45 |
| RIDADR | UN 3261 8/PG 1 |
| WGK Germany | 3 |
| HS Code | 2931599090 |
