≥95% , 2390041-82-2

Synonym(s):
Diazo biotin-azide

CAS NO.：2390041-82-2

Empirical Formula: C33H45N9O7S

Molecular Weight: 711.84

MDL number: MFCD28334530

PRODUCT Properties

• storage temp.: -20°C
• form: powder or crystals

Description and Uses

Diazo Biotin-PEG3-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Diazo allows efficient release of captured biotinylated molecules from streptavidin using sodium dithionite (Na2S2O4).

Azo biotin-azide is a linker that contains a biotin moiety connected to an azide group through a spacer arm containing a diazo group that can be cleaved with 50 mM sodium dithionite solution. The biotin can be captured by streptavidin and the azide can react with terminal or strained alkynes.