1869922-24-6

CAS NO.：1869922-24-6

Empirical Formula: C35H52N6O12S

Molecular Weight: 780.89

MDL number: MFCD28505551

PRODUCT Properties

• Boiling point: 1023.8±65.0 °C(Predicted)
• Density: 1.245±0.06 g/cm3(Predicted)
• storage temp.: -20°C
• pka: 10.58±0.46(Predicted)
• InChIKey: HRHZIAGPIYYJMG-MJUSKHNJSA-N
• SMILES: C(OC(C1=CC(OC)=C(OCCCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@H]2[C@@]3([H])NC(=O)N[C@@]3([H])CS2)C=C1[N+]([O-])=O)C)(=O)NCC#C

Description and Uses

PC Biotin-PEG3-alkyne is useful for introducing a biotin moiety to azide-containing biomolecules using Cu(I)-catalyzed Click Chemistry. PEG spacer provides better solubility to the labeled molecules in aqueous media. Captured biomolecules can be efficiently photoreleased using near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

PC biotin-alkyne is an azide-reactive photoclevable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to an alkyne group through a spacer arm containing a photocleavable moiety. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low-intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm²).