Arachidonic-5,6,8,9,11,12,14,15-d8acid , ≥98atom%D,≥98%(CP) , 69254-37-1

Synonym(s):
cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic acid-5,6,8,9,11,12,14,15-d₈

CAS NO.：69254-37-1

Empirical Formula: C20H32O2

Molecular Weight: 304.47

MDL number: MFCD00065888

PRODUCT Properties

• Melting point: -49 °C(lit.)
• Boiling point: 169-171 ;°C/0.15 ;mmHg(lit. )
• Density: 0.945 g/mL at 25 °C
• Flash point: -16 °C
• storage temp.: -20°C
• solubility: 0.1 M Na2CO3: 1.7 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: Miscible
• form: methyl acetate solution
• color: Colorless to light yellow
• Stability: Light Sensitive, Temperature Sensitive

Description and Uses

Arachidonic acid-d₈ contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of arachidonic acid by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.

Arachidonic Acid-d8 is the deuterated form of Arachidonic Acid (A765000), which is an essential fatty acid and a precursor in biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in the liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and it is also a constituent of animal phosphatides.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H319-H336
• Precautionary statements: P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
• Hazard Codes: F,Xi
• Risk Statements: 11-36-66-67-19
• Safety Statements: 16-26-29-33
• RIDADR: UN 1231 3/PG 2
• WGK Germany: 1