S3817451
phyproof ReferenceSubstance , 465-39-4
Synonym(s):
14,15-β-epoxy-3-β-hydroxy-5-β-bufa-20,22-dienolide;Bufogenin;RBG;Recibufogenin;Respigon
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB4215.54 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 113-140°/155-168° |
| alpha | D22 -7.1° (c = 1.259 in chloroform); D16 -5.4° (c = 2.030 in chloroform) |
| Boiling point: | 431.17°C (rough estimate) |
| Density | 1.0474 (rough estimate) |
| refractive index | 1.4860 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMF: 25 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL; DMSO: 20 mg/mL; Ethanol: 5 mg/mL |
| form | White to off-white solid. |
| pka | 15.14±0.70(Predicted) |
| color | White to off-white |
| Stability: | Moisture Sensitive |
Description and Uses
As one of the active components of Bufonis bufa, Resibufogenin is speculated that Etobufaxin can inhibit the proliferation of tumor cells by inducing apoptosis of osteosarcoma cells.
Resibufogenin is used for content determination/identification/pharmacological experiments, etc.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H300+H310+H330 |
| Precautionary statements | P260-P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310 |
| Safety Statements | 24/25 |
| RIDADR | 3172 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| HS Code | 29322090 |
| Toxicity | LD50 oral in mouse: 59800mg/kg |
