(-)-Epinephrine , 98% , 51-43-4
Synonym(s):
(−)-Adrenalin;(−)-Epinephrine;(R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol;L -Adrenaline;L -Epinephrine
CAS NO.：51-43-4
Empirical Formula: C9H13NO3
Molecular Weight: 183.2
MDL number: MFCD00002204
EINECS: 200-098-7
PRODUCT Properties
| Melting point: | 215 °C (dec.)(lit.) |
| Boiling point: | 316.88°C (rough estimate) |
| alpha | -51.5 º (c=4, 1M HCl, dry sub) |
| Density | 1.1967 (rough estimate) |
| refractive index | -51.5 ° (C=4, 1mol/L HCl) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, in ethanol (96 per cent) and in methylene chloride. It dissolves in hydrochloric acid. |
| pka | 8.66(at 25℃) |
| form | Fine Crystalline Powder |
| color | White to light beige |
| optical activity | -53.222～25 (c 1.2, 0.5 mol dm-3 HCl)-50.617 (c 7.5, 0.37 mol dm-3 HCl), L +50.5 (HCl) |
| Water Solubility | <0.01 g/100 mL at 18 ºC |
| Decomposition | > 212°C |
| Sensitive | Air & Light Sensitive |
| Merck | 14,3619 |
| BRN | 2368277 |
| Stability: | Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. Light sensitive. |
Description and Uses
The combination of the catechol nucleus, the β-hydroxyl group, and the N-methyl give EPI a direct action and a strong affinity for all adrenergic receptors. Epinephrine and all other catechols are chemically susceptible to oxygen and other oxidizing agents, especially in the presence of bases and light, quickly decomposing to inactive quinones. Therefore, all catechol drugs are stabilized with antioxidants and dispensed in air-tight amber containers.
L-Adrenaline (Epinephrine) belongs to a group of the compounds known as catecholamines, which play an important role in the regulation of physiological process in living organisms. The antioxidant activity and antioxidant mechanism of L-adrenaline was cla
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301+H331-H310 |
| Precautionary statements | P261-P262-P280-P301+P310-P302+P352+P310-P304+P340+P311 |
| Hazard Codes | T |
| Risk Statements | 23/24/25-52/53-36/37/38-33 |
| Safety Statements | 36/37/39-45-61-26-23 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | DO2625000 |
| F | 8-10-23 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29373100 |
| Toxicity | LD50 i.p. in mice: 4 mg/kg (Lands) |
