BeclomethasoneSolution , 1.00mg/ml , 4419-39-0

Synonym(s):
9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione;9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione

CAS NO.：4419-39-0

Empirical Formula: C22H29ClO5

Molecular Weight: 408.92

MDL number: MFCD00135614

EINECS: 224-585-9

PRODUCT Properties

• Melting point: 217- 222°C (dec.)
• Boiling point: 600.2±55.0 °C(Predicted)
• Density: 1.35±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Dioxane (Sparingly, Sonicated), DMSO (Sparingly), Ethyl Acetate (Slightly), Methane
• form: Solid
• pka: 12.17±0.70(Predicted)
• color: White to Pale Beige
• Merck: 13,1020
• Stability: Hygroscopic

Description and Uses

Beclomethasone dipropionate is claimed to exert a topical effect on the lungs without significant systemic activity. It is used by inhalation, generally from a metered aerosol, for the prophylaxis of the symptoms of asthma.

Beclomethasone has been used in MS?MS (mass spectrometry) methods for the analysis of β-agonists, corticosteroids, chloramphenicol and penicillins. It has also been used to find the differential response of glucocorticoids in larval regeneration model.

Safety

• Symbol(GHS): GHS08
• Signal word: Warning
• Hazard statements: H361
• Precautionary statements: P201-P202-P281-P308+P313-P405-P501
• Safety Statements: 24/25
• WGK Germany: 3
• HS Code: 29372900