A0795912
ambroxol , 99% , 18683-91-5
CAS NO.：18683-91-5
Empirical Formula: C13H18Br2N2O
Molecular Weight: 378.1
MDL number: MFCD00242702
EINECS: 242-500-3
| Pack Size | Price | Stock | Quantity |
| 1G | RMB271.20 | In Stock |
|
| 5G | RMB1079.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 233-234 C |
| Boiling point: | 468.6±45.0 °C(Predicted) |
| Density | 1.5863 (rough estimate) |
| refractive index | 1.6220 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Soluble in Water. |
| form | solid |
| pka | 15.12±0.40(Predicted) |
| color | White |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months. |
| CAS DataBase Reference | 18683-91-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Ambroxol(18683-91-5) |
Description and Uses
Ambroxol HCl (18683-91-5) is a radical scavenger with anti-inflammatory activity. Blocks the generation of reactive oxygen species by bronchoalveolar lavage cells, inhibits doxorubicin-induced lipid peroxidation (70 mg/kg in rat), and inhibits the release of inflammatory mediators from human leukocytes and mast cells (effective dose ~ 100 μM)
Ambroxol is a metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug. Free base of Ambroxol Hydrochloride (A575900).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319-H315-H302-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 36-26 |
| WGK Germany | 3 |
| RTECS | GV8423000 |
| Toxicity | guinea pig,LD50,intraperitoneal,280mg/kg (280mg/kg),Medicamentos de Actualidad. Vol. 15, Pg. 523, 1979. |
