Brainnatriureticpeptide-32human , ≥97%(HPLC) , 114471-18-0

CAS NO.：114471-18-0

Empirical Formula: C143H244N50O42S4

Molecular Weight: 3464.04

MDL number: MFCD00133149

PRODUCT Properties

• storage temp.: −20°C
• solubility: ≥206.6 mg/mL in DMSO
• form: powder
• Sequence: H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH(Disulfide bridge Cys10-Cys26)

Description and Uses

B-type natriuretic peptide is the only cardiac natriuretic peptide common to all vertebrate species thus far examined. The plasma BNP level is used as a robust and reliable biomarker for the diagnosis and prognosis of heart failure. BNP was isolated in 1988 from porcine brain extracts and was thus named the brain natriuretic peptide. Soon thereafter, BNP was found to be expressed abundantly in the cardiac ventricle and scarcely in the brains of humans and rats. Currently, BNP has been recognized as a principal cardiac hormone and referred to as the B-type natriuretic peptide.

hemostatic, antimicrobial

Safety

• WGK Germany: 3