PRODUCT Properties
Melting point: | 177-177.5 °C |
Boiling point: | 508.4±50.0 °C(Predicted) |
Density | 1.296±0.06 g/cm3(Predicted) |
pka | 7.29±0.20(Predicted) |
Description and Uses
Arborinine is a potent and orally activeLSD1 inhibitor. Arborinine increases the expression of H3K4me1/2, H3K9me1/2, E-cad protein and decreases the expression of UBE2O protein level. Arborinine induces cell cycle arrest at S phase. Arborinine shows antitumor activity [1][2].