5''-O-DMT-2''-O-(2-methoxyethyl)uridine3''-CEphosphoramidite , 98% , 163759-97-5

CAS NO.：163759-97-5

Empirical Formula: C42H53N4O10P

Molecular Weight: 804.86

MDL number: MFCD11505866

PRODUCT Properties

• storage temp.: 4°C, protect from light
• pka: 9.39±0.10(Predicted)
• form: Solid
• color: White to off-white
• InChIKey: ZLOKLUONKGURQI-LWTSSKLSNA-N
• SMILES: O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,36,42,r|

Description and Uses

2'-O-MOE-U-3'-phosphoramidite (DMT-2'-O-MOE-rU Phosphoramidite) is a 2'-O-MOE-protected nucleoside phosphoramidite that can be inserted into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances stability, resists nuclease, and exhibits low toxicity for improved genetic manipulation.