2'-OMe-ibu-G Phosphoramidite , 95% , 150780-67-9

Synonym(s):
DMT-2′-O-Me-rG(ib) amidite;N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-guanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS NO.：150780-67-9

Empirical Formula: C45H56N7O9P

Molecular Weight: 869.94

MDL number: MFCD16876397

EINECS: 2017-001-1

PRODUCT Properties

• Melting point: 138 - 140°C
• storage temp.: Inert atmosphere,2-8°C
• solubility: Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly, Sonicated)
• form: powder
• pka: 9.16±0.20(Predicted)
• color: white to off-white
• InChIKey: IRRDHRZUOZNWDJ-MLLDKZSOSA-N
• SMILES: O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,47,r|

Description and Uses

2''-OMe-ibu-G Phosphoramidite (CAS# 150780-67-9) is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand.

Safety

• WGK Germany: 3