M8193647
GDC-0575 , 98% , 1196504-54-7
CAS NO.：1196504-54-7
Empirical Formula: C16H21BrClN5O
Molecular Weight: 414.73
MDL number: MFCD32669797
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB3744.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
Description and Uses
GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.
