M8125747
PQR530 , 98% , 1927857-61-1
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB6317.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 660.7±65.0 °C(Predicted) |
| Density | 1.338±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.33 mg/ml; DMSO: 10 mg/ml |
| form | A crystalline solid |
| pka | 5.05±0.10(Predicted) |
| color | Light yellow to yellow |
Description and Uses
PQR530 is a potent, ATP-competitive, orally bioavailable and brain-penetrant dual pan-PI3K/mTORC1/2 inhibitor, with a subnanomolar Kd toward PI3Kα and mTOR (0.84 and 0.33 nM, respectively). Antitumor activity[1][2].
