PQ 401 , ≥99% , 196868-63-0

Synonym(s):
IGF-1R Inhibitor II;IGF-1R Inhibitor II, PQ401 - CAS 196868-63-0 - Calbiochem;N-(2-Methoxy-5-chlorophenyl)-Nʹ-(2-methylquinolin-4-yl)-urea, PQ401;N-(5-Chloro-2-methoxyphenyl)-N′-(2-methylquinolin-4-yl)urea

CAS NO.：196868-63-0

Empirical Formula: C18H16ClN3O2

Molecular Weight: 341.79

MDL number: MFCD00160558

PRODUCT Properties

• Density: 1.370±0.06 g/cm3 (20 ºC 760 Torr)
• storage temp.: Sealed in dry,2-8°C
• solubility: DMSO: >10mg/mL
• form: White solid
• color: white

Description and Uses

PQ 401, a novel diarylurea compound, is an inhibitor of insulin-like growth factor 1 receptor (IGF-1R) autophosphorylation. Also used as a potential testing agent in the treatment of breast and other IGF-1-sensitive cancers.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: T
• Risk Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3