M8102647
UBP301 , 98% , 569371-10-4
CAS NO.：569371-10-4
Empirical Formula: C15H14IN3O6
Molecular Weight: 459.19
MDL number: MFCD06411591
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1865.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 214.1-214.4 °C(Solv: water (7732-18-5)) |
| Boiling point: | 636.1±65.0 °C(Predicted) |
| Density | 1.98±0.1 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | DMSO: 0.5 mg/ml (w/ gentle warming) |
| form | A crystalline solid |
| pka | 2.12±0.10(Predicted) |
Description and Uses
UBP 301 is an antagonist of the kainate receptor, an ionotropic glutamate receptor (apparent Kd = 5.94 μM). It displays ~30-fold selectivity over AMPA receptors. UBP 301 is used to assess the roles of kainate receptors in neuronal signaling, particularly in reference to neuropathic pain.
UBP 301 is an antagonist of kainate receptors. UBP 301 is the N3-4-carboxybenzyl substituted analog II of Willardiine, which was found to be equipotent at AMPA and GLUK5-containing kainate receptors in the neonatal rat spinal cord.
