ProstaglandinJ2(PGJ2) , 98% , 60203-57-8

CAS NO.：60203-57-8

Empirical Formula: C20H30O4

Molecular Weight: 334.45

MDL number: MFCD00065804

EINECS: 201-185-2

PRODUCT Properties

• Boiling point: 521.7±50.0 °C(Predicted)
• Density: 1.103±0.06 g/cm3(Predicted)
• storage temp.: −20°C
• solubility: DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-.DEL
• pka: 4.75±0.10(Predicted)
• form: Liquid
• color: Colorless to light yellow

Description and Uses

Prostaglandin J₂ (PGJ₂) is formed from PGD₂ by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ₂ inhibits platelet aggregation with an IC₅₀ of about 5-10 nM. PGJ₂ has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines. However, this activity has been attributed to further metabolites of PGJ₂ and not the parent compound itself.

PGJ2 (Prostaglandin J2) is a Prostaglandin D2 metabolite that has shown potent anti-neoplastic and antiviral activity.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H319-H336
• Precautionary statements: P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
• Hazard Codes: Xn,Xi,F
• Risk Statements: 20/21/22-36/37/38-67-66-36-11
• Safety Statements: 26-36-33-29-16