(±)15-HEPE , 98% , 88852-33-9
| Pack Size | Price | Stock | Quantity |
| 50μg | RMB3424.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 488.0±45.0 °C(Predicted) |
| Density | 0.997±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml |
| pka | 4.75±0.10(Predicted) |
Description and Uses
(±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE . 15(S)-HEPE is formed from EPA via a 15(S)-HpEPE intermediate, which is produced by 15-lipoxygenase (15-LO) and reduced by glutathione peroxidase (GPX).1,2 (±)15-HEPE is active against P. acnes and S. aureus (MICs = 128 and 512 mg/L, respectively).3 It inhibits aggregation of isolated rat neutrophils induced by the formyl peptide receptor agonist fMLP (IC50 = 4.7 μM).4 Bronchoalveolar lavage fluid (BALF) levels of (±)15-HEPE are increased in patients with allergic asthma or COVID-19.5,6
(±)15-HEPE is an ester product.
Safety
| Symbol(GHS) |  GHS02 |
| Signal word | Danger |
