LeukotrieneA3methylester(LTA3methylester) , 98% , 83851-38-1

CAS NO.：83851-38-1

Empirical Formula: C21H34O3

Molecular Weight: 334.49

MDL number: MFCD00065894

PRODUCT Properties

• Flash point: -26 °C
• storage temp.: −20°C
• solubility: DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml
• form: Colorless liquid.

Description and Uses

Biosynthesis of LTA₃ occurs from 5,8,11-eicosatrienoic acid via the 5-LO pathway and it is the putative intermediate in the biosynthesis of 3-series leukotrienes. LTA₃ as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

LTA3 (Leukotriene A3 methyl ester) is a suicide inhibitor of LTA4 hydrolase.

Safety

• Symbol(GHS): GHS02,GHS07,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H225-H304-H315-H336-H361f-H373-H411
• Precautionary statements: P201-P210-P273-P301+P310-P308+P313-P331
• Hazard Codes: F,Xn,N
• Risk Statements: 11-38-48/20-51/53-62-65-67
• Safety Statements: 36/37-61-62-16
• RIDADR: UN 1208 3/PG 2
• WGK Germany: 3