PKGInhibitor , 98% , 82801-73-8

CAS NO.：82801-73-8

Empirical Formula: C38H74N18O10

Molecular Weight: 943.11

MDL number: MFCD00080098

PRODUCT Properties

• Density: 1.50±0.1 g/cm3(Predicted)
• storage temp.: −20°C
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• form: Solid
• pka: 3.16±0.10(Predicted)
• color: White to off-white
• Water Solubility: Soluble in water at 1mg/ml

Description and Uses

PKG inhibitor is a specific cGMP-dependent PKG inhibitor (K_i = 86 μM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells.

A reversible substrate competitive inhibitor for protein kinase G. The sequence corresponds to a non-phosphorylatable analog of histone H2B.

Safety

• WGK Germany: 3