6-ketoProstaglandinF1α-d4(6-ketoPGF1α-d4) , 98% , 82414-64-0

CAS NO.：82414-64-0

Empirical Formula: C20H34O6

Molecular Weight: 370.49

MDL number: MFCD00135270

PRODUCT Properties

• solubility: DMF: >100 mg/ml (from 6-keto PGF1a); DMSO: >50 mg/ml (from 6-keto PGF1a); Ethanol: >16 mg/ml (from 6-keto PGF1a); PBS pH 7.2: >3.3 mg/ml (from 6-keto PGF1a

Description and Uses

6-keto Prostaglandin F_1α-d₄ (6-keto PGF_1α-d₄) contains four deuterium atoms at the 3, 3'', 4, and 4'' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF_1α by GC- or LC-MS. 6-keto PGF_1α is the inactive, non-enzymatic hydrolysis product of PGI₂. 6-keto PGF_1α serves as a useful marker of PGI₂ biosynthesis in vivo. When [³H]-PGI₂ is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [³H]-6-keto PGF_1α.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger