cis-trismethoxyResveratrol(cis-TrimethoxyStilbene) , 98% , 94608-23-8

CAS NO.：94608-23-8

Empirical Formula: C17 H18 O3

Molecular Weight: 270.32

MDL number: MFCD11977725

PRODUCT Properties

• Melting point: 55-57 °C
• Boiling point: 423.8±35.0 °C(Predicted)
• Density: 1.104±0.06 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: ≤50mg/ml in DMSO;50mg/ml in dimethyl formamide
• form: solution in ethanol.
• color: Colorless to light yellow
• CAS DataBase Reference: 94608-23-8

Description and Uses

Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities. In addition, resveratrol activates sirtuins and, in yeast, extends lifespan. cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells. It inhibits tubulin polymerization in a dose-dependent manner (IC₅₀ = 4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine. trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.

cis-trismethoxy Resveratrol is a potent antioxidant found in grapes and red wine. Also, it is a resveratrol analog with increased antiproliferative activity towards a number of cancer cell lines.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
• Hazard Codes: Xi
• Risk Statements: 41
• Safety Statements: 26-39