PRODUCT Properties
Melting point: | 163-165 °C(lit.) |
Boiling point: | 466.0±25.0 °C(Predicted) |
Density | 1.367±0.06 g/cm3(Predicted) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 3.66±0.10(Predicted) |
color | White to Off-White |
Water Solubility | >21.55 mg/mL in Water with ultrasonic; |
Stability: | Hygroscopic |
Description and Uses
2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
WGK Germany | 2 |
RTECS | MC0555300 |
HazardClass | IRRITANT |