Home Categories Calcimycinhemimagnesium
M7482558

Calcimycinhemimagnesium , ≥98% , 72124-77-7

Synonym(s):
A23187 hemimagnesium salt;Antibiotic A 23187 hemimagnesium salt;Calcimycin hemimagnesium salt;Calimycin hemimagnesium salt

CAS NO.:72124-77-7

Empirical Formula: C58H72MgN6O12

Molecular Weight: 1069.55

MDL number: MFCD00151203

Pack Size Price Stock Quantity
5g RMB5760.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

storage temp.  2-8°C
solubility  acetone: 5 mg/mL, clear, faintly yellow
BRN  6765085

Description and Uses

Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis[1][2][3][4].

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36/37
WGK Germany  3
8

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