Propargyl-PEG6-NH2 , 97% , 1198080-04-4
| Pack Size | Price | Stock | Quantity |
| 5g | RMB6368.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 401.8±40.0 °C(Predicted) |
| Density | 1.058±0.06 g/cm3(Predicted) |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 8.74±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Description and Uses
Propargyl-PEG6-amine is a crosslinker with a hydrophilic PEG spacer which can increase the hydrophilicity of the molecule in aqueous environment. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry.
Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
