VilazodoneD8? , 98% , 1794789-93-7
CAS NO.：1794789-93-7
Empirical Formula: C26H26N5O2
Molecular Weight: 440.517
MDL number: MFCD28900708
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB4742.40 | In Stock |
|
| 5mg | RMB20160.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 195-198°C |
| storage temp. | Refrigerator |
| solubility | Water: 0.32 mg/ml |
| form | A solid |
| color | White to off-white |
Description and Uses
Vilazodone-d8 is intended for use as an internal standard for the quantification of vilazodone by GC- or LC-MS. Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively). It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg, respectively. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.
Labelled Vilazodone (V265000). It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.
