M6121535
Tetrahydrobiopterin , ≥98% , 17528-72-2
Synonym(s):
(6R)-BH4
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1248.00 | In Stock |
|
| 10mg | RMB2144.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >202°C (dec.) |
| Boiling point: | 506.6±60.0 °C(Predicted) |
| Density | 1.89±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly) |
| form | Solid |
| pka | 14.22±0.20(Predicted) |
| color | White to Off-White |
| Stability: | Hygroscopic |
Description and Uses
Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| Toxicity | mouse,LD50,intraperitoneal,258mg/kg (258mg/kg),Toxicology. Vol. 42, Pg. 183, 1986. |
