PRODUCT Properties
Melting point: | 320°C |
Boiling point: | 450.55°C (rough estimate) |
alpha | D20 +54° (c = 0.5 in pyridine) |
Density | 1.1396 (rough estimate) |
refractive index | 1.5600 (estimate) |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | Powder |
pka | 10.24±0.40(Predicted) |
Description and Uses
This base has been isolated from Rauwolfia serpentina and is an isomer of Ajmalinine (q.v.). Pharmacologically it has between three and four times the effect of the total Rauwolfia alkaloids on isolated rabbit uterus and is very specific. In the cat, the blood pres~ure is lowered by 0.5-2.0 mgm per kilo body weight. The toxicity is low.
Safety
RIDADR | 1544 |
HazardClass | 6.1(b) |
PackingGroup | III |