PRODUCT Properties
| Melting point: | 135-136℃ |
| Boiling point: | 491.8±45.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| pka | 14.31±0.20(Predicted) |
Description and Uses
One of three closely related alkaloid isolated from Securinega suffructicosa, the base has [α]17D + 58.2° (c 0.14, CHC13) or + 50° (dioxan). It yields a crystalline picrate, m.p. l86-7°C (dec.), and a 3: 5-dinitrobenzoate, m.p. 198-9°C;[α]17D + 55.3° (c 0.10, CHC13). On hydrogenation with Pt02 in AcOH it gives the dihydro derivative, forming a hydrochloride, m.p. 241- 2°C. When treated with methylsulphonyl chloride in pyridine, the base furnishes viroallosecurinine, m.p. 133- 4°C; [α]D + 1200° (c 0.01, EtOH).
