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A6959258

Diacerein , 10mMinDMSO , 13739-02-1

Synonym(s):
1,8-Diacetoxy-3-carboxyanthraquinone

CAS NO.:13739-02-1

Empirical Formula: C19H12O8

Molecular Weight: 368.29

MDL number: MFCD00468030

EINECS: 237-310-2

Pack Size Price Stock Quantity
1ml RMB559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 217-2180C
Boiling point: 631.5±55.0 °C(Predicted)
Density  1.491±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Sparingly), Methanol (Slightly)
pka 3.01±0.20(Predicted)
form  Solid
color  Light Yellow to Yellow
Water Solubility  240μg/L at 25℃
Merck  14,2960
InChIKey TYNLGDBUJLVSMA-UHFFFAOYSA-N
LogP 3.126 (est)

Description and Uses

Diacerein is a disease-modifying antirheumatic drug (DMARD), reported to be useful in the treatment of various inflammatory conditions, including osteoarthritis. It forms water soluble chelates with calcium and copper, acting ultimately to reduce the activity of lysosomal enzymes and decrease the formation of rheumatoid factor.

Treatment of Osteoarthritis (Prevent cartilage destruction)

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  CB8781000
HS Code  29146990
Toxicity rat,LD50,unreported,7500mg/kg (7500mg/kg),Drugs of the Future. Vol. 4, Pg. 445, 1979.

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